What examinations do I need to do for soft chancre?

What tests do I need to perform for chancroid? Chancroid is often transmitted through sexual intercourse. There are more men, and women have mild symptoms or become carriers. Although chancroid carriers do not get sick, they can infect others and are the most dangerous source of infection. So what tests do patients with soft chancre need to undergo to make a diagnosis?
Soft chancre needs to be differentiated from syphilis hard chancre, genital herpes chastity sissy , venereal lymphogranuloma, fixed drug eruption, Behcet's disease dildo hero , etc. At the same time, infectious diseases such as syphilis, AIDS, and hepatitis should be detected.
Examination method for soft chancre:
(1) Bacteriological examination
Haemophilus is a gram-negative bacterium. The culture conditions show polymorphic characteristics and susceptibility to contamination. This bacterium has no spores and no movement.
1. Microscopic examination: When smears are taken from open ulcers of chancre and stained, Haemophilus dureli is easy to detect. When the unbroken lesion is punctured from an abscess or a horizontal ridge, the puncture fluid is also easy to detect and stained with smear specimens. More typically, use methylene blue staining or Gram staining to observe with 10×100 times oil immersion.
2. Culture and inspection: It is difficult to isolate and cultivate chancre bacteria, so when taking specimens, attention should be paid to taking the pus stored under the edge of the chancre ulcer or the pus sucked by puncturing the horizontal flap, or fully washing the bottom of the ulcer with physiological saline, and then applying the specimen with a wet cotton swab of physiological saline for cultivation.
(2) Serological testing
Infection with Haemophilus cankrei can produce antibodies, which can be confirmed through serological examination, whether it is complement fixation, agglutination reaction girl using vibrator , and indirect fluorescent antibody method, but it has not been promoted. Currently, the sensitivity of IgM antibodies is believed to be 74%, and the sensitivity of IgG antibodies is 94%, and its specificities are 84% and 64%, respectively. The accuracy of this method needs to be improved.
(3) PCR detection of Haemophilus dukrei. This method detects bacterial DNA and has been widely used in scientific research, but no reagent is available for clinical diagnosis.
(4) Histopathological changes
The pathological manifestations are ulcer in the center, epidermal hyperplasia at the edge of the ulcer, and three inflammatory zones can be seen below the ulcer, arranged vertically. They are: basal layer of the ulcer: mainly polymorphonuclear leukocytes, mixed with red blood cells, cellulose and necrotic tissue. There are many new blood vessels in the middle layer, obvious tissue edema, infiltration of neutrophils, lymphocytes and histiocytes magic wands , and many fibroblasts can be seen. In the deep layer, there is diffuse infiltration of lymphocytes and plasma cells, and obvious around the blood vessels.
The examination of patients with soft chancre can be based on the history of sexual contact before the onset, especially the history of unclean sexual intercourse, typical clinical manifestations and course, soft and flat papules, pustules, ulcers after a short incubation period, and unilateral suppurative lymphadenitis. Haemophilus durei can be detected through direct microscopy and culture, and the DNA of Haemophilus durei can be detected by PCR.
Realistic dildo | best vibrator | pvc dildo | fat pocket pussy

• What disease is vulva white spot?
• What if men insist on a short period of time? How short is abnormal?