Precocious puberty can be divided into true precocious puberty and pseudo precocious puberty.

Precocious puberty is more common in girls. The incidence of idiopathic precocious puberty in girls is about 9 times higher than that in boys, while the incidence of central nervous system abnormalities (such as tumors) is higher in boys.

"precocious puberty" before the age of 6 is more common in girls, which is mainly characterized by breast development. once parents find a lump or induration in a girl's breast, they should take their child to the hospital endocrinology specialist in time.

Precocious puberty is divided into true and false, pseudoprecocious puberty only refers to the precocious development of simple breast, penis, axillary hair or pubic hair, while true precocious puberty refers to the real onset of puberty, which is generally caused by the increase of gonadotropin secreted by hypothalamus and pituitary, which is characterized by the acceleration of height growth, the enlargement of uterus and ovary in girls and the enlargement of testicles in boys.

In order to accurately distinguish between true and false cock cages , doctors will first check the child's bone age and gynecological B-ultrasound (if it is a girl).

In the process of sexual development, both boys and girls are related to the rapid growth of height and weight and the acceleration of bone maturation. due to the excessive growth of bones, the epiphyseal fusion is earlier, although the early height is higher than that of children of the same age, but the height is shorter in adulthood. After puberty, except that the height is shorter than the general population, all the others are normal.

The sexual development process of peripheral precocious puberty is very different from the above-mentioned law. Boys with precocious puberty should pay attention to the size of testes giant dildo , if testis-gt;3ml, suggest central precocious puberty, such as testis is not enlarged best dildo , but masculine progressive development, then suggest peripheral precocious puberty, its androgen may come from adrenal gland. Patients with intracranial tumors only show precocious puberty in the course of the disease, and they only appear in the localization signs such as increased intracranial pressure and visual field defect in the later stage, so it is necessary to be vigilant.

In order to diagnose whether a girl has precocious puberty, it must pass a series of tests and tests.

80% of precocious puberty is 90% of physical problems, there is no obvious cause, so there is no special drug treatment. The only alternative methods are injection of long-acting medroxyprogesterone or oral medroxyprogesterone, which are not drugs for self-use and must be treated scientifically in the endocrinology department of a large hospital.

In addition to taking examination and treatment measures, parents should pay special attention to their children's psychological changes and tell their children some necessary knowledge after a clear diagnosis to help them adapt to the new changes in their bodies. Therefore, it is an urgent task for parents to protect their children. At the same time, you should also be prepared, because some precocious puberty lacks effective treatment, so you have to rely on the careful care of your parents. At present, some children's nutrition and health food on the market contains hormone ingredients, eating too much can lead to precocious puberty, which should attract the attention of parents.

It is found that children have unilateral or bilateral breast development, first of all, we should fully understand the relevant situation of children, and judge whether it is simple breast development or true precocious puberty. If it is for breast development, do not worry too much, but be careful not to take tonics to your child in the future. At the same time, you should strengthen observation, keep in touch with your child care doctor and receive guidance.

What are the good ways to treat precocious puberty

(1) etiological treatment

Patients with tumor should be removed by surgery or chemotherapy, thyroid preparations should be given to correct thyroid function caused by radiotherapy and hypothyroidism, and patients with congenital adrenocortical hyperplasia can be treated with corticosteroids.

(2) Drug treatment

1. Gonadotropin-releasing hormone analogue (GnRHa)

Natural GnRH is a polypeptide of 10 amino acids. at present, several GnRHa are long-acting synthetic hormones formed by replacing glycine with D-tryptophan, D-serine, D-histidine and D-leucine. Its function is to reduce the secretion of pituitary gonadotropin and restore estrogen to the level of prepuberty. 0.1mg/kg can be injected intramuscularly every 4 weeks, after treatment, the sexual development and height growth of the patients, bone age maturity can be controlled, its effect is reversible male chastity cages , if the treatment as soon as possible can improve the final adult height.

2. Gonadal hormone

Its mechanism is to use high-dose sex hormone feedback to inhibit hypothalamic-pituitary gonadotropin secretion. For example, medroxyprogesterone, also known as medroxyprogesterone, is a progesterone derivative, which is used for precocious puberty in girls. The daily oral dose is 10~30mg. Cyproterone is a derivative of 17-hydroxyprogesterone, which can not only block the sex hormone receptor, but also reduce the release of gonadotropin, daily 70-150mg/m2, the above two drugs can not improve the adult height.
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