The world's first confirmed cure of AIDS from infection to death

In 2007 gay masturbation , Timothy Brown, from the United States, who suffers from both white blood and AIDS, was treated by Dr. Huth, an oncology and hematology specialist in Berlin. Huth recalls that Brown was almost on the brink of death. After observation, Huth decided to have a bone marrow transplant to cure leukemia first. After more than 3 years of clinical observation, Huth found that the transplant also cured Brown's AIDS best penis pump , becoming the world's first confirmed cure of AIDS.

The investigation found that the original bone marrow donors not only match very well, but also contain mutated genes that can naturally resist HIV in bone marrow, but this gene exists only in a small number of Nordic humans. This makes the first living example to prove that AIDS can be cured is not appreciated by most scientists, and it is generally believed that an example like Brown is difficult to replicate, and his recovery includes a variety of coincidences. for example penis vibrator , some genetic mutations that may exist in Brown's body coincide with bone marrow stem cell transplantation and play a positive role in fighting the virus. Here's how to judge AIDS by its early symptoms.

Initial symptoms of AIDS

Some patients have no clinical symptoms at the initial stage of HIV infection, but most of them have clinical symptoms caused by HIV viremia and acute injury of immune system from 6 to 6 weeks after HIV infection. the main symptoms in the initial stage of AIDS are:

1. Symptoms of respiratory tract infection: fever, fatigue, sore throat, general discomfort and other symptoms of upper respiratory tract infection.

2. Headache and rash: individual have headache, rash, meningoencephalitis or acute polyneuritis

3. Lymph nodes: enlarged lymph nodes in neck, axilla and occipital, similar to infectious mononucleosis.

4. Hepatosplenomegaly.

The process of AIDS patients from onset to death

Two kinds of glycoproteins, gp120 and gp41, are embedded in the lipoprotein envelope of HIV in vitro. Gp120 has affinity with CD4 glycoprotein on the surface of lymphocytes and can specifically bind to it. Gp41 mediates the fusion of virus envelope and host cell membrane. Therefore sexshop , HIV can selectively invade CD4+ lymphocytes after reaching the blood through skin and mucous membrane damage or other pathways such as blood.

After HIV invades CD4+ lymphocytes, under the action of viral reverse transcriptase, DNA is synthesized and integrated into the chromosomes of host cells. The integrated viral DNA can replicate in the cell, form a complete virion and release outside the cell, die, infect new cells, or show latent infection, and enter the offspring cells with cell division.

At the initial stage of infection, HIV replicated in large quantities, resulting in viremia and the expression of capsid antigen p24. The clinical manifestation was acute HIV infection. Due to the large number of intracellular replication of HIV, CD4+ lymphocytes were damaged and died, and CD4+T cells decreased significantly. However, under the immune action of the body, CD8+CTL is activated to kill HIV infected cells and produce anti-HIV antibodies at the same time, viremia is quickly cleared and the number of CD4+ lymphocytes increases.

However, HIV was not completely killed and entered a state of persistent latent infection. HIV was replicated at a low level, and the clinical manifestation was asymptomatic HIV infection. With the continuous replication and spread of HIV, CD4+ lymphocytes continue to die, which leads to the depletion of CD4+ lymphocytes, serious destruction of immune function, infection of various conditional pathogenic bacteria and tumors, clinical manifestations of AIDS, and finally death.
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