Introduction to the routine treatment of gonorrhea through what can it be transmitted?

Gonorrhea is a sexually transmitted disease caused by Neisseria gonorrhoeae (Neisseria gonorrhoeae), which is mainly characterized by suppurative infection in the genitourinary system. Its incidence ranks second among sexually transmitted diseases in China. Neisseria gonorrhoeae is gram-negative diplococcus, it is not easy to survive without the human body, and it is easy to be killed by general disinfectants. Gonorrhea occurs mostly in sexually active young men and women.

Gonorrhea has an obvious increasing trend in the world in recent years. Gonorrhea has returned to life in China since 1975 bad dragon dildo , and the number of patients has increased linearly year by year, which is the main disease of venereal diseases. In recent years, with the sharp increase in syphilis cases, gonorrhea cases showed a downward trend year by year. However bbw ass , gonorrhea is still a common sexually transmitted disease in China, and it is also a Class B infectious disease that needs to be prevented and treated in the Law of the people's Republic of China on the Prevention and treatment of Infectious Diseases.

What on earth can gonorrhea spread?

1. Transmission through sexual contact

99% of gonorrhea in adults, especially men, is 100% sexually transmitted. The speed of transmission is fast, and the infection rate is very high, which can occur 3-5 days after infection. Most of the infected people were young and middle-aged.

At present, FSWs are the main source of infection in our country. Survey data show that among patients with gonorrhea, the infection rate of one-time intercourse between men and women is 22% Mel 35%; the infection rate of both men and women is that men are easy to transmit to women.

2. Non-sexual contact infection

This situation is rare, mainly contact with gonococcal secretions or contaminated appliances, such as towels with secretions, foot cloth foot basins, clothing panty vibrator , and even toilet seats can be contagious. Especially women (including young girls) are prone to infection because of their short urethra and reproductive tract.

Introduction to routine treatment of gonorrhea

1. General therapy

(1) sexual isolation: sexual life is prohibited.

(2) rest: std patients with high fever and severe complications should have a proper rest and stay in bed if necessary.

(3) maintain the balance of water, electrolytes, sugar and water compounds and supplement a high-sugar, high-protein diet.

2. Systemic therapy

(1) Evaluation and indication of gonorrhea drugs: there are many drugs for gonorrhea, but they should be selected on the principle of high efficiency, safety and suitable price.

① penicillins: play a bactericidal effect by destroying the synthesis of the bacterial wall. These drugs are suitable for the treatment of gonorrhea caused by non-penicillinase-resistant Neisseria gonorrhoeae (ppng). It is the standard treatment of ldquo; (rdquo;). However, it is not appropriate to do a drug sensitivity test before treatment, and it is not appropriate to use it as a routine treatment. When the prevalence of ppng strains is more than 5%, penicillins should not be used, but other preparations should be selected. The purpose of adding probenecid is to slow down the excretion of penicillin from kidney, reduce its binding to plasma protein, increase blood level and prolong half-life, so as to give full play to its antibacterial effect.

② beta;- lactamase inhibitors: the resistance of strain ppng to penicillin and some cephalosporins is mainly due to the production of beta;- lactamases. Clavulanic acid and penicillane sulfone are compounds with weak antibacterial activity. When combined with antibiotics containing beta;- lactam ring horse dildo , clavulanic acid and penicillane sulfone can inhibit the growth of ppng strains by inhibiting-lactamase and protecting antibiotics from destruction, but they do not play a significant role in non-ppng strains.

The pharmacokinetic characteristics of clavulanic acid and penicillane sulfone are similar to amoxicillin (ampicillin) and ampicillin (ampicillin) respectively.

③ aminoglycosides and aminocyclic glycols: the main function is to inhibit the synthesis of bacterial proteins. It is used to treat patients who are resistant or allergic to penicillin. The first group is commonly used gentamicin (gentamycin), kanamycin (kanamycin), amikacin (amikacin) and netilmicin (ethylsiloxacin); the latter is mainly spectinomycin (gonorrhea), which has a cure rate of more than 98% for simple gonorrhea caused by ppng and non-ppng strains, and has excellent efficacy in the treatment of complicated gonorrhea. Moreover, the drug does not produce cross-resistance with penicillin and cephalosporins, so it is safe to use, and it is one of the best drugs for the treatment of gonorrhea.

At present, spectinomycin-resistant Neisseria gonorrhoeae strains have appeared in some areas. The antibacterial spectrum of its replacement product trospectomycin is wider, including gram positive bacteria, negative bacteria, anaerobes and chlamydia trachomatis. Moreover, it has higher tissue concentration and longer half-life, so it has a better effect on gonorrhea and chlamydial urethritis.
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