How to treat pudendal herpes

How to treat pudendal herpes? The disease is self-limited and can be cured in about 1-2 weeks. the purpose of treatment is to prevent the next relapse. at present, there is no specific drug for the disease. the principle of treatment is to shorten the course of the disease, prevent secondary infection and reduce recurrence.

one. Local therapy:

The principle is to dry, converge, protect the affected area and prevent secondary infection. You can apply 2% gentian purple solution, or choose 10% bismuth gallate (Dematuo dermatol), zinc oxide ointment or paste, Arnebia elm ointment, 0.5% neomycin ointment, or 0.25% herpes 0.1% IDU ointment, 5% herpes net dimethyl sulfoxide solution for skin herpes, etc. 10% aluminum acetate or zinc-copper mixture can also be used on the face.

two. Systemic treatment:

One of the principles of treatment is that infected HSV cannot be activated or even eliminated. Second, to regulate immunity and prevent recurrence, acyclovir can be used intravenously or orally, lizhuwei oral, interferon Ⅱ intramuscular injection, we in the treatment of recurrent genital herpes, the use of interferon 3 million units of intramuscular injection produced by the Biotechnology Center of the fourth Medical University, once a day, 10 times as a course of treatment, a total of three courses of treatment women vibrator , properly combined with the use of interleukin Ⅱ or Rebedo or colistin, 95% of the patients did not relapse.

three. Pathogen therapy

(1) acyclovir (acyclovir): it can selectively inhibit virus replication, reduce the occurrence of new damage, relieve pain, shorten the time of wound healing and detoxification, oral administration of primary or primary GH,0.2g, 5 times a day for 7 days. For recurrent GH,0.2g, oral administration, 5 times a day, for 5 days, or 0.4 g, 3 times a day, for 5 days, or 0.8 g, twice a day for 5 days, and 1~1.6g/d for mild patients, 5 times a day for 5 days. Severe patients with 15mg/ (kg ·d), intravenous injection for 5-7 days, dehydration and renal insufficiency should be used cautiously. In recent years, acyclovir (ACV) derivatives such as valaciclovir (valaciclovir) and famciclovir (famciclorvir) have also been used in the treatment of this disease.

(2) Sodium phosphonoformate: for patients with TK gene deficiency who are resistant to ACV virus infection, sodium phosphonoformate 40mg/kg can be injected intravenously, once every 8 hours, until cured.

(3) ribavirin (ribavirin): 0.6~0.8g/d, orally or intramuscularly, for 5-7 days.

(4) α, β and γ-interferon (α, β, γ-IFN): 1 million U / d for 5 ~ 7 days.

(5) poly-myocytic 2~4ml was injected intramuscularly every other day for 5-7 days.

(6) cytarabine (cytarabine) can also be used.

four. immunotherapy

Straus et al were vaccinated with gD-2 vaccine, that is, the glycoprotein D expressed by recombinant HSV-2 in CHO cells, the antigen-specific neutralizing antibody induced was equal to or higher than that produced by GH patients, 100 μ g each time, and repeated once after 2 months. Compared with the control group, the frequency of recurrence was significantly reduced, and it was also effective in relieving symptoms and preventing infection.

five. Local therapy

Care should be taken to protect the wound, keep it clean, dry and prevent secondary bacterial infection. 5% acyclovir (ACV) ointment or emulsion, α or β interferon emulsion or gel, 1% methyl violet (gentian purple) solution, 3% tetracycline ointment or 25% zinc oxide oil can be used.

six. Symptomatic therapy

If secondary bacterial infection, should be appropriate antibiotics, if the pain is severe can be given painkillers.

seven. The handling of sexual partners

Since most sexual partners may already be infected with HSV, they should also be tested and treated if necessary.

eight. Traditional Chinese medicine therapy

(1) damp-heat downward injection type:

Treatment: clearing heat and promoting dampness, and detoxification.

Prescription: Longdan Xiegan decoction

(2) liver and kidney deficiency type:

Treatment: clearing heat and resolving dampness, nourishing the liver and kidney.

Prescription: Zhibai Dihuang pill combined with Zhenghui osmosis decoction.
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