How to check for tertiary syphilis?

How to check for tertiary syphilis? Syphilis is a chronic sexually transmitted disease that is mainly transmitted through sexual intercourse. It can cause damage to multiple organs throughout the body. Syphilis can be divided into three phases according to its severity. If syphilis develops into three phases in women, it may be passed on to the next generation through the placenta. Causes congenital syphilis in newborns, which is extremely harmful. So what tests should be done to confirm that syphilis has developed to stage three?

Tertiary syphilis generally requires a comprehensive physical examination, including the skin, mucosa magic wands , bones, mouth wand vibrator , vulva, anus and superficial lymph nodes of the whole body. Elderly people in the disease should undergo cardiovascular and nervous system examinations. Other specific inspections are as follows.

Examination methods for tertiary syphilis:

1. Treponema pallidum examination.

2. Dark field microscopy: At the skin lesions, use a glass slide to scrape tissue exudate or lymph node puncture fluid, and see active Treponema pallidum.

3. Immunofluorescence staining: Green Treponema pallidum can be seen under a fluorescence microscope.

4. Syphilis serum test.

5. Depending on the antigen used, syphilis serum tests are divided into the following two categories:

(1) Non-treponema pallidum antigen serum test, in which cardiolipin is used as antigen to determine anti-cardiolipin antibodies, also known as reagins magic wands , in serum.

(1) Rapid plasma reagin test: It is an improvement of VDRL antigen. The sensitivity and specificity are similar to VDRL. The advantage is that the results can be read with the naked eye;

(2) The unheated serum reagin slide test is also a modification of VDRL antigen, and its sensitivity and specificity are similar to those of VDRL.

(2) Treponema pallidum antigen serum test

(1) Fluorescent syphilis helix antibody absorption test: This method is a more sensitive and specific spirochete test;

(2) Three-stage Treponema pallidum hemagglutination test: It has high sensitivity and specificity, and is simple to operate, but it is not as sensitive as the FTA-ABS test for first-stage syphilis.

Do you understand how to check for tertiary syphilis? If you find yourself feeling unwell, you should go to the hospital in time for a detailed examination. Once you are diagnosed, you should receive syphilis treatment in time.
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